General Information

  • ID:  hor001085
  • Uniprot ID:  NA
  • Protein name:  Hydra-RFamide 4
  • Gene name:  NA
  • Organism:  Hydra vulgaris
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  HLRGRF
  • Length:  6
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T6 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001085_AF2.pdbhor001085_ESM.pdb

Physical Information

Mass: 87428 Formula: C35H56N14O7
Absent amino acids: ACDEIKMNPQSTVWY Common amino acids: R
pI: 12.5 Basic residues: 3
Polar residues: 1 Hydrophobic residues: 2
Hydrophobicity: -100 Boman Index: -2566
Half-Life: 3.5 hour Half-Life Yeast: 10 min
Half-Life E.Coli: >10 hour Aliphatic Index 65
Instability Index: 2628.33 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  8954943
  • Title:  Isolation of Four Novel Neuropeptides, the hydra-RFamides I-IV, From Hydra Magnipapillata